Yahya Hama

Differentiated AML cells into macrophage-like cells using reprogramming factor overexpression in combination with hypomethylating agents. Assessed differentiation and functional activity through flow cytometry and IncuCyte-based readouts.

Followed an established protocol to generate dendritic-like cells, including cDC1, cDC2, and pDC subsets, and assessed their cytokine production using ELISA. The project focused on identifying ways to enhance cytokine production and functional activity.

Investigated thymus homing mechanisms using a combined in vivo and in vitro experimental model. Performed bone marrow transplantation experiments and subsequent in vitro culture of thymus-derived cells to support detection and analysis of donor cell homing.

Processed and imaged pig brain tissue samples for IHC analysis, contributing to research on acute lung injury and transplantation.

Assisted team in collecting human donor lung tissue samples to facilitate critical research initiatives.

Investigated cytokine-mediated disruption of IL-10 regulation in T cells, testing IL-6, IL-18, and IL-15 as contributors to inflammatory conditions in ANCA-associated vasculitis patient serum.