Wesam Bazzar

Experienced researcher in molecular biology with a focus on cancer biology and therapeutics. With over 9 years of hands-on experience, I have a proven track record in designing, performing, and managing scientific experiments. Expertise in interpreting and analyzing scientific data, as well as presenting and publishing results in peer-reviewed scientific journals. Thrives on new challenges and excels at managing diverse projects within an interdisciplinary environment. Works effectively with competent and focused teams, known for proactive nature, capability, and resourcefulness.

• MYCN Amplification Is Associated with Reduced Expression of Genes Encoding γ-Secretase Complex and NOTCH Signaling Components in Neuroblastoma, Agarwal P, Glowacka A, Mahmoud L, Bazzar W, Larsson LG, Alzrigat M, Int J Mol Sci, 05/02/23, 24, 9, 8141, 10.3390/ijms24098141, 37175848
• MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner, Castell A, Yan Q, Fawkner K, Bazzar W, Zhang F, Wickström M, Alzrigat M, Franco M, Krona C, Cameron DP, Dyberg C, Olsen TK, Verschut V, Schmidt L, Lim SY, Mahmoud L, Hydbring P, Lehmann S, Baranello L, Nelander S, Johnsen JI, Larsson LG, Cancer Res Commun, 03/31/22, 2, 3, 182-201, 10.1158/2767-9764.CRC-21-0019, 36874405
• Methods to Study Myc-Regulated Cellular Senescence: An Update, Zhang F, Bazzar W, Alzrigat M, Larsson LG, Methods Mol Biol, 2318, 241-254, 10.1007/978-1-0716-1476-1_12, 34019294
• Pharmacological inactivation of CDK2 inhibits MYC/BCL-XL-driven leukemia in vivo through induction of cellular senescence, Bazzar W, Bocci M, Hejll E, Högqvist Tabor V, Hydbring P, Grandien A, Alzrigat M, Larsson LG, Cell Cycle, 01/01/21, 20, 1, 23-38, 10.1080/15384101.2020.1855740, 33356836
• A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation, Castell A, Yan Q, Fawkner K, Hydbring P, Zhang F, Verschut V, Franco M, Zakaria SM, Bazzar W, Goodwin J, Zinzalla G, Larsson LG, Sci Rep, 07/03/18, 8, 1, 10064, 10.1038/s41598-018-28107-4, 29968736
• Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival, Langenkamp E, Zhang L, Lugano R, Huang H, Elhassan TE, Georganaki M, Bazzar W, Lööf J, Trendelenburg G, Essand M, Pontén F, Smits A, Dimberg A, Cancer Res, 11/01/15, 75, 21, 4504-16, 10.1158/0008-5472.CAN-14-3636, 26363010